Penetration Testing Tangerang City Web Application With Implementing OWASP Top 10 Web Security Risks Framework

The speed of technological development has made it possible for all people to be connected to one another. The creation of web-based information systems that help in all areas, including government, health, and education, is one of the forces behind the development of technology. With these technological advancements, websites are susceptible to cybercrimes that could end in the theft of crucial data. Top 10 Web Application Security Risks is the most effective prevention process for decrease company information leaks. On the website tangerangkota.go.id, the researcher will conduct a test using the Top 10 Web Application Security Risks technique. Top 10 Web Application Security Risks consist of Broken Access Control, Cryptographic Failures, Injection, Insecure Design, Security Misconfiguration, Vulnerable and Outdated Components, Identification and Authentication Failures, Software and Data Integrity Failures, Security Logging and Monitoring Failures, Server-Side Request Forgery. The penetration testing results found on the Tangerang City website which are 4 injections, 2 broken access controls, 1 security misconfiguration

LA EDUCACIÓN A DISTANCIA: UNA MIRADA EN LA UNIVERSIDAD DE GRANMA, CUBA

Distance education has become in recent years in an educational practice very useful, motivated largely by the development achieved by the Information and Communication Technologies, facilitating participation in educational programs that are not accessible by old fashion way. It is described the evolution of the mode of reference in the world and its progress. This work aimed to show the emergence and development of distance education at the University of Granma, Cuba and its impact on the professionals. The main results of the training were presented to distance mediated technologies master's degrees, diplomas and courses at international, national and local level. The results showed a very good achievement gratification in postgraduate programs and high professional level of the facilitators is highlighted. It was concluded that distance education at the graduate is effective at the University of Granma, can lead to new opportunities in overcoming the human capital of the territory and the country and internationally, allowing capacity building to enhance the productive activity and promote development.La educación a distancia se ha convertido en los últimos años en una práctica educativa de gran utilidad, motivado en gran medida por el desarrollo alcanzado de las Tecnologías de la Información y las Comunicaciones, facilitando la participación a programas educativos a los que no es posible acceder por la vía tradicional. Se describió la evolución de la modalidad de referencia en el mundo y sus avances. El presente trabajo, tuvo como objetivo mostrar el surgimiento y desarrollo de la educación a distancia en la Universidad de Granma, Cuba y su impacto en los profesionales. Se presentaron los principales frutos de la capacitación a distancia mediada por las tecnologías en maestrías, diplomados y cursos a escala internacional, nacional y territorial. Los resultados reflejaron una muy buena complacencia de los logros de posgrados efectuados y se resalta el alto nivel profesional de los facilitadores. Se concluyó que la educación a distancia en el postgrado es efectiva en la Universidad de Granma, puede propiciar nuevas oportunidades en la superación del capital humano del territorio y del país e internacionalmente, permitiendo crear capacidades para mejorar la actividad productiva e impulsar desarrollo

Resultados de la conización con asa diatérmica como procedimiento diagnóstico y terapéutico

Introduction: currently broadcasts the use of diathermy handles for the treatment of premalignant lesions of the neck.Objective: to present the results of loop diathermy conization in cervical premalignant lesions. Material and methods: a cross-sectional descriptive study was conducted in the “Mariana Grajales" Gynecoobstetric Hospital form January 2010 to December 2012 It was formed a sample of 1 310 patients who underwent conization and studied some variables as: age, histological result conization, surgical margins and complications. Results: between 35-39 years of age were affected 269 (20.5 %) patients were diagnosed 349 (26.6 %) with cervical intraepithelial neoplasia II and was a significant association between cervical intraepithelial neoplasia III and the age group of 25 - 59 with (X2 = 32.7 p = 0.000) occurred only 52 (4.0 %) cases of affected edges and 37 (2.8 %) complications.Conclusions: the most affected age was 35-39 years; the most common diagnosis was cervical intraepithelial neoplasia III and was little affected edges and frequency of postoperative complications.Introducción: actualmente se difunde el uso de las asas diatérmicas para el tratamiento de las lesiones premalignas de cuello. Objetivo: exponer los resultados de la conización con asa diatérmica en las lesiones premalignas de cuello. Meterial y método: se realizó un estudio transversal y descriptivo en el Hospital Ginecoobstétrico “Mariana Grajales” de enero de 2010 a diciembre de 2012. Se conformó la muestra con las 1 310 pacientes a las que se les realizó una conización y se estudiaron variables como la edad, el resultado histológico de la conización, los bordes quirúrgicos y las complicaciones. Resultados: entre los 35-39 años de edad fueron afectadas 269 (20.5%) pacientes, se diagnosticaron 349 (26.6%) con neoplasias intraepitaliales cervicales II y hubo una asociación significativa entre la neoplasias intraepitaliales cervicales III y el grupo de edad de 25-59 años con (X2=32.7 y p=0.000), solo se presentaron 52 (4.0%) casos de bordes afectados y 37 (2.8%) de complicaciones. Conclusiones: la edad más afectada fue de 35-39 años, el diagnóstico más frecuente fue la neoplasias intraepitaliales cervicales III y hubo poca frecuencia de bordes afectados y de complicaciones postoperatorias

Factores asociados al fracaso escolar en estudiantes de medicina del Policlínico Facultad Vicente Ponce Carrasco Factors associated to school failure in medicine students at the University Policlinic Vicente Ponce Carrasco

Se realizó una investigación con el objetivo de caracterizar los factores asociados al fracaso escolar en 54 estudiantes de Medicina, de nacionalidad china, en la segunda avanzada del Policlínico Facultad Vicente Ponce Carrasco, en el Nuevo Programa de Formación de Médicos, polo de Jagüey Grande, en la asignatura Morfofisiología Humana I. Para la realización del trabajo se utilizaron modelos de investigación cualitativos/cuantitativos. Se caracterizó el fracaso escolar en los estudiantes, identificándose factores externos tales como la falta de motivación e interés por la carrera que estudian, poca motivación en el desarrollo de las actividades docentes, el estudiar solo, el insuficiente tiempo dedicado al estudio independiente, y el uso de la lectura y memorización como única técnica de estudio. Entre los factores internos se detectaron la procedencia sociodemográfica, inadecuada orientación del profesor durante el desarrollo de las actividades docentes, insuficiente orientación y control de las tareas docentes por parte del profesor, y consecuentemente, la poca utilidad de las mismas por parte de los estudiantes.We developed an investigation with the objective of characterizing factors associated to school failure in 54 medicine Chinese students in the second group at the University Policlinic Vicente Ponce Carrasco in the New Program of Physician's Formation, Jagüey Grande Pole, in the matter Human Morphophysiology I. To carry out this study we used qualitative-quantitative investigative models. School failure in students was characterized, identifying external factors as lack of motivation and interest in the specialty they study, poor motivation in developing school activities, studying alone, insufficient time dedicated to independent study, and the usage of reading and memorization as unique study technique. Among the internal factors: sociodemographic precedence, inadequate orientation of the teachers during the development of school activities, insufficient orientation and control of the school tasks by the teacher, and consequently their little utility for students

Pharmacological Approaches for the Modulation of the Potassium Channel KV4.x and KChIPs

Ion channels are macromolecular complexes present in the plasma membrane and intracellular organelles of cells. Dysfunction of ion channels results in a group of disorders named channelopathies, which represent an extraordinary challenge for study and treatment. In this review, we will focus on voltage-gated potassium channels (KV), specifically on the KV4-family. The activation of these channels generates outward currents operating at subthreshold membrane potentials as recorded from myocardial cells (ITO, transient outward current) and from the somata of hippocampal neurons (ISA). In the heart, KV4 dysfunctions are related to Brugada syndrome, atrial fibrillation, hypertrophy, and heart failure. In hippocampus, KV4.x channelopathies are linked to schizophrenia, epilepsy, and Alzheimer’s disease. KV4.x channels need to assemble with other accessory subunits (β) to fully reproduce the ITO and ISA currents. β Subunits affect channel gating and/or the traffic to the plasma membrane, and their dysfunctions may influence channel pharmacology. Among KV4 regulatory subunits, this review aims to analyze the KV4/KChIPs interaction and the effect of small molecule KChIP ligands in the A-type currents generated by the modulation of the KV4/KChIP channel complex. Knowledge gained from structural and functional studies using activators or inhibitors of the potassium current mediated by KV4/KChIPs will better help understand the underlying mechanism involving KV4-mediated-channelopathies, establishing the foundations for drug discovery, and hence their treatments.Ministerio de Ciencia e Innovacion (MICIU) Spain SAF201675021-R PID2019-104366RB-C21 RTI2018-097189-B-C22 PID2019-104366RBC22Instituto de Salud Carlos III CIBERCV program CB/11/00222Consejo Superior de Investigaciones Cientificas (CSIC) PIE 201820E104 2019AEP148 201880E109European Fund for Economic and Regional Development (FEDER)Spanish Ministry of Economy, Industry, and Competitivity (MINECO)Consejo Superior de Investigaciones Cientificas (CSIC) BES-2017-080184 FPU2017/02731Department of Atomic Energy (DAE)CUNY Research Scholars ProgramCollegiate Science Technology Entry Program (CSTEP)Hostos Office of Academic AffairsCSIC Open Access Publication Support Initiative through its Unit of Information Resources for Research (URICI

A Latin American survey on demographic aspects of hospitalized, decompensated cirrhotic patients and the resources for their management

Introduction & objectives: Liver cirrhosis is a major cause of mortality worldwide. Adequate diagnosis and treatment of decompensating events requires of both medical skills and updated technical resources. The objectives of this study were to search the demographic profile of hospitalized cirrhotic patients in a group of Latin American hospitals and the availability of expertise/facilities for the diagnosis and therapy of decompensation episodes. Methods: A cross sectional, multicenter survey of hospitalized cirrhotic patients. Results: 377 patients, (62% males; 58 ± 11 years) (BMI > 25, 57%; diabetes 32%) were hospitalized at 65 centers (63 urbans; 57 academically affiliated) in 13 countries on the survey date. Main admission causes were ascites, gastrointestinal bleeding, hepatic encephalopathy and spontaneous bacterial peritonitis/other infections. Most prevalent etiologies were alcohol-related (AR) (40%); non-alcoholic-steatohepatitis (NASH) (23%), hepatitis C virus infection (HCV) (7%) and autoimmune hepatitis (AIH) (6%). The most frequent concurrent etiologies were AR + NASH. Expertise and resources in every analyzed issue were highly available among participating centers, mostly accomplishing valid guidelines. However, availability of these facilities was significantly higher at institutions located in areas with population > 500,000 (n = 45) and in those having a higher complexity level (Gastrointestinal, Liver and Internal Medicine Departments at the same hospital (n = 22). Conclusions: The epidemiological etiologic profile in hospitalized, decompensated cirrhotic patients in Latin America is similar to main contemporary emergent agents worldwide. Medical and technical resources are highly available, mostly at great population urban areas and high complexity medical centers. Main diagnostic and therapeutic approaches accomplish current guidelines recommendations

Anuario del Centro de Estudios Martianos (Vol. 32 2009)

El Anuario del Centro de Estudios Martianos es la publicación insignia de esta institución y heredera directa del Anuario Martiano de la Biblioteca Nacional José Martí, que se publicó entre 1969 y 1977, bajo la dirección del poeta y ensayista Cintio Vitier.<br> Desde que salió a la luz su primera entrega, en 1978, se han publicado treinta y cinco números, en los que aparecen artículos y ensayos de importantes estudiosos de la vida y obra del Apóstol, en Cuba y el resto del mundo.<br> En sus secciones fijas (Otros textos de José Martí, Documentos, Estudios y aproximaciones, Vigencias, Publicaciones, Bibliografía, Constante) y los apartados especiales, los lectores pueden conocer disímiles temas del quehacer martiano internacional, en el año que termina además de mantenerse al tanto de las últimas contribuciones de los promotores e investigadores de la obra martiana en el orbe